[Frustrated Phagocytosis Logo] Science of the Health Effects of Fibers

Scientific Papers


 

This page summarizes a number of papers by the authors, most of which are available here as the complete text with all tables and graphs. Each such paper is available in two ways, the first for convenient reading with a browser while connected to the web, and the other as a zip'ed file containing the complete text of the paper with all tables, images, and auxillary data files for download. When unzip'ed into a suitable directory on your computer, this latter method allows you to obtain a complete copy of the paper for browsing without being connected to the web.

There are, of course, many more important scientific papers in this field, many of which are cited throughout these pages, but those summarized here are the ones that we, the authors, are free to make available here.

Papers about the connection between fiber dissolution rate and biopersistence and disease

Do Vitreous Fibers Break in the Ling? by W. Eastes, P. A. Baron, R. E. Baier, M. Guldberg, and R. Potter. Originally published in 2007 by Inhalation Toxicology 19, 311-315.
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Dissolution of fibers inhaled by rats by W. Eastes, and J. G. Hadley, J. G. 1995. Originally published in 1995 by Inhalation Toxicology 7, 179-196.

A mathematical model of fiber carcinogenicity and fibrosis in inhalation and intraperitoneal experiments in rats by W. Eastes and J. G. Hadley. Originally published in 1996 by Inhalation Toxicology 8, 323-343.
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Dissolution of fibers inhaled by rats by W. Eastes, and J. G. Hadley, J. G. 1995. Originally published in 1995 by Inhalation Toxicology 7, 179-196.

Dissolution of glass fibers in the rat lung following intratracheal instillation by W. Eastes, K. J. Morris, A. Morgan,K. A. Launder,C. G. Collier, J. A. Davis, S. M. Mattson, and J. G. Hadley. Originally published in 1995 by Inhalation Toxicology, 7, 197-213.
Read the paper or Download it (58 kB).

Papers about estimating fiber dissolution rate from composition or from biopersistence studies

Estimating in-vitro glass fiber dissolution rate from composition by W. Eastes, R. M. Potter, and J. G. Hadley. Originally published in 2000 by Inhalation Toxicology 12, 269-280.
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Estimating rock and slag wool fiber dissolution rate from composition by W. Eastes, R. M. Potter, and J. G. Hadley. To be published in 2000 by Inhalation Toxicology.
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Estimation of dissolution rate from in-vivo studies of synthetic vitreous fibers by W. Eastes, R. M. Potter, and J. G. Hadley. To be published in 2000 by Inhalation Toxicology.
Read the paper or Download it (40 kB).

Papers about measuring fiber dissolution rate in vitro

In-vitro acellular method for determining fiber durability in simulated lung fluid by J. Bauer, S. M. Mattson, and W. Eastes. Originally available in 1997 from the authors.
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Method for determination of in-vitro fiber dissolution rate by direct optical measurement of diameter decrease by R. M. Potter. Originally published in 2000 by Glastechnische Berichte 73, 46-55.
Read the paper or Download it (63 kB).

Glass fiber dissolution in simulated lung fluid and measures needed to improve consistency and correspondence to in-vivo dissolution by S. Mattson. Originally published in 1994 by Environmental Health Perspectives 102 (suppl. 5), 87-90.

Glass fibers in simulated lung fluid: Dissolution behavior and analytical requirements by S. Mattson. Originally published in 1994 by Annals of Occupational Hygiene 38, 857-877.

Glass fiber dissolution in a physiological saline solution by R. M. Potter and S. M. Mattson. Originally published in 1991 by Glastechnische Berichte 64,16-28.

Papers about airborne fiber exposures

Airborne glass fiber concentrations during installation of residential insulation by T. R. Jacob, J. G. Hadley, J. R. Bender, and W. Eastes. Originally published in 1992 by American Industrial Hygiene Association Journal 53, 519-523.

Airborne glass fiber concentrations during manufacturing operations involving glass wool insulation by T. R. Jacob, J. G. Hadley, J. R. Bender, and W. Eastes. Originally published in 1992 by American Industrial Hygiene Association Journal 54, 320-326.

Papers about fiber properties and manufacturing methods

Man-made vitreous fibers: Nomenclature, Chemistry, and Physical Properties by the TIMA Nomenclature Committee, W. Eastes, editor. Originally published in 1991 by the Thermal Insulation Manufacturers Association (TIMA) and now out of print.
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